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Biomolecular Constructs as Building Blocks of Soft Nanoscale Materials NU 2017-032 INVENTORS SonBinh Nguyen* Nathaniel Rosi* (Univ of Pittsburgh) SHORT DESCRIPTION A highly tunable assembly platform that enables the modular synthesis of programmable peptide-oligonucleotide chimeras to assemble into vesicles or 1D fibres. BACKGROUND Few classes of material building blocks exhibit the programmability offered by nucleic... Published: 12/20/2023   |   Inventor(s):   Keywords(s): Technologies Category(s): Technology Classifications > Therapeutics

Biomolecular Constructs as Building Blocks of Soft Nanoscale Materials NU 2017-032 INVENTORS SonBinh Nguyen* Nathaniel Rosi* (Univ of Pittsburgh) SHORT DESCRIPTION A highly tunable assembly platform that enables the modular synthesis of programmable peptide-oligonucleotide chimeras to assemble into vesicles or 1D fibres. BACKGROUND Few classes of material building blocks exhibit the programmability offered by nucleic... Published: 4/12/2021   |   Inventor(s):   Keywords(s): Technologies Category(s): Technology Classifications > Therapeutics, State > Illinois, Region > Midwest

Blockmir Technology to Selectively Up Regulate Therapeutic Targets and Neutralise Disease-Associated microRNA Activity Overview Mirrx Therapeutics A/S is commercializing innovative ”Blockmir” oligonucleotide technology, a proprietary therapeutic paradigm with potential to (i) enhance the protein expression of previously undruggable targets, and (ii) neutralise pathological microRNA expression via selective blockade of microRNA-based gene regulation. Blockmir Blockmir... Published: 6/7/2024   |   Inventor(s): David Bauer, Melissa Acosta Keywords(s): Biomaterials, Technologies, Therapeutics Category(s): Technology Classifications > Therapeutics, Agriculture > Abandoned Material, Technology Classifications > Diagnostics